Gene Name	G2E3
Gene ID	55632
Gene Full Name	G2/M-phase specific E3 ubiquitin protein ligase
Gene Alias	KIAA1333|PHF7B
Transcripts	ENSG00000092140
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Cytosol;Golgi apparatus, Vesicles;
Membrane Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q7L622
HGNC ID	HGNC:20338
OMIM ID	611299
Summary	Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in apoptotic process and protein ubiquitination. Predicted to act upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000034	chr14	4239	2192	1168	7599	View
6007125	chr14	57	2	0	59	View
6010288	chr14	6	26	0	32	View
6010289	chr14	6	26	0	32	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - G2E3 peak across samples

Peak Plot