Gene Information
|
Gene Name
|
GABRG3 |
|
Gene ID
|
2567
|
|
Gene Full Name
|
gamma-aminobutyric acid type A receptor subunit gamma3 |
|
Gene Alias
|
- |
|
Transcripts
|
ENSG00000182256
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Microtubules;Nucleoli; 
|
|
Membrane Info
|
FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q99928
|
|
HGNC ID
|
HGNC:4088
|
|
OMIM ID
|
600233 |
|
Summary
|
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012] |
Target gene [GABRG3] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6010647 |
chr15 |
27 |
3 |
0 |
30 |
View |
| 6014437 |
chr15 |
16 |
0 |
0 |
16 |
View |
| 6015194 |
chr15 |
1 |
4 |
10 |
15 |
View |
| 6026414 |
chr15 |
2 |
0 |
0 |
2 |
View |
| 6027435 |
chr15 |
1 |
1 |
0 |
2 |
View |
| 6029618 |
chr15 |
1 |
0 |
0 |
1 |
View |
| 6029619 |
chr15 |
1 |
0 |
0 |
1 |
View |
Target gene [GABRG3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - GABRG3 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
