HTLV1 Target gene Detail Information

> GFRA2 Gene Search Result


Gene Information
Gene Name GFRA2
Gene ID 2675
Gene Full Name GDNF family receptor alpha 2
Gene Alias GDNFRB|NRTNR-ALPHA|NTNRA|RETL2|TRNR2
Transcripts ENSG00000168546
Virus HTLV1
Gene Type protein-coding
HPA Location Info Plasma membrane;Vesicles;Intracellular and membrane;
Membrane Info Predicted intracellular proteins
Uniport_ID O00451
HGNC ID HGNC:4244
OMIM ID 601956
Summary Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Target gene [GFRA2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6018114 chr8 2 7 0 9 View
6018115 chr8 2 7 0 9 View
6018150 chr8 2 7 0 9 View
6019216 chr8 5 3 0 8 View
6020026 chr8 5 2 0 7 View

Target gene [GFRA2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - GFRA2 peak across samples

Peak Plot