HTLV1 Target gene Detail Information

> GLI2 Gene Search Result


Gene Information
Gene Name GLI2
Gene ID 2736
Gene Full Name GLI family zinc finger 2
Gene Alias CJS|HPE9|PHS2|THP1|THP2
Transcripts ENSG00000074047
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nucleoli;Centrosome, Basal body;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P10070
HGNC ID HGNC:4318
OMIM ID 165230
Summary This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Target gene [GLI2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000360 chr2 945 538 509 1992 View
6000963 chr2 277 53 348 678 View
6010650 chr2 26 4 0 30 View
6013694 chr2 14 4 0 18 View
6022818 chr2 3 2 0 5 View
6033584 chr2 27 28 5 60 View
6033585 chr2 13 4 0 17 View
6033586 chr2 2 5 3 10 View
6033587 chr2 51 88 86 225 View
6033588 chr2 52 21 44 117 View
6033589 chr2 127 167 17 311 View
6033590 chr2 8 0 0 8 View
6033591 chr2 7 3 0 10 View
6033592 chr2 24 47 38 109 View
6033593 chr2 65 3 0 68 View
6033594 chr2 78 116 7 201 View

Target gene [GLI2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - GLI2 peak across samples

Peak Plot