Gene Name	GLIS3
Gene ID	169792
Gene Full Name	GLIS family zinc finger 3
Gene Alias	NDH|ZNF515
Transcripts	ENSG00000107249
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Golgi apparatus, Primary cilium;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q8NEA6
HGNC ID	HGNC:28510
OMIM ID	610192
Summary	This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003090	chr9	146	16	5	167	View
1012129	chr9	7	0	0	7	View
1016284	chr9	1	0	0	1	View
1022933	chr9	1	0	0	1	View
1043429	chr9	8	0	0	8	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
GSE270937	DNA methylation sequencing	35	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - GLIS3 peak across samples

Peak Plot

> Dataset: GSE68402 - GLIS3 peak across samples

Peak Plot

> Dataset: GSE270130 - GLIS3 peak across samples

Peak Plot

> Dataset: GSE100400 - GLIS3 peak across samples

Peak Plot

> Dataset: GSE131257 - GLIS3 peak across samples

Peak Plot