Gene Information
|
Gene Name
|
GMDS |
|
Gene ID
|
2762
|
|
Gene Full Name
|
GDP-mannose 4,6-dehydratase |
|
Gene Alias
|
GMD|SDR3E1 |
|
Transcripts
|
ENSG00000112699
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Enzymes, Metabolic proteins, Predicted intracellular proteins |
|
Uniport_ID
|
O60547
|
|
HGNC ID
|
HGNC:4369
|
|
OMIM ID
|
602884 |
|
Summary
|
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009] |
Target gene [GMDS] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6009222 |
chr6 |
4 |
4 |
30 |
38 |
View |
| 6020553 |
chr6 |
6 |
0 |
0 |
6 |
View |
| 6020577 |
chr6 |
6 |
0 |
0 |
6 |
View |
| 6021062 |
chr6 |
2 |
2 |
2 |
6 |
View |
| 6022395 |
chr6 |
5 |
0 |
0 |
5 |
View |
Target gene [GMDS] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - GMDS peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
