Gene Name	GUCY1A2
Gene ID	2977
Gene Full Name	guanylate cyclase 1 soluble subunit alpha 2
Gene Alias	GC-SA2|GUC1A2
Transcripts	ENSG00000152402
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info
Membrane Info	Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins
Uniport_ID	P33402
HGNC ID	HGNC:4684
OMIM ID	601244
Summary	Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6013798	chr11	11	7	0	18	View
6016558	chr11	8	4	0	12	View
6020350	chr11	7	0	0	7	View
6020961	chr11	4	2	0	6	View
6029178	chr11	1	0	0	1	View
6030310	chr11	1	0	0	1	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - GUCY1A2 peak across samples

Peak Plot