HTLV1 Target gene Detail Information

> HDAC8 Gene Search Result


Gene Information
Gene Name HDAC8
Gene ID 55869
Gene Full Name histone deacetylase 8
Gene Alias CDA07|CDLS5|HD8|HDACL1|KDAC8|MRXS6|RPD3|WTS
Transcripts ENSG00000147099
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q9BY41
HGNC ID HGNC:13315
OMIM ID 300269
Summary Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Target gene [HDAC8] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6023167 chrX 3 1 0 4 View

Target gene [HDAC8] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - HDAC8 peak across samples

Peak Plot