Gene Name	HECW1
Gene ID	23072
Gene Full Name	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Gene Alias	NEDL1
Transcripts	ENSG00000002746
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoli fibrillar center;Cytosol;
Membrane Info	Enzymes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID	Q76N89
HGNC ID	HGNC:22195
OMIM ID	610384
Summary	Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in regulation of dendrite morphogenesis and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002813	chr7	76	40	91	207	View
6003972	chr7	82	33	19	134	View
6017902	chr7	7	2	1	10	View
6029746	chr7	1	0	0	1	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - HECW1 peak across samples

Peak Plot