Gene Name	IFNG
Gene ID	3458
Gene Full Name	interferon gamma
Gene Alias	IFG|IFI|IMD69
Transcripts	ENSG00000111537
Virus	VZV
Gene Type	protein-coding
HPA Location Info	Secreted to blood;
Membrane Info	Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID	P01579
HGNC ID	HGNC:5438
OMIM ID	147570
Summary	This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	34960186	S593A	gE	ORF68		I T	View
2	34960186	S595A	gE	ORF68		I T	View
3	34960186	T596A	gE	ORF68		I T	View
4	34960186	T598A	gE	ORF68		I T	View
5	34960186	Y569A	gE	ORF68		I T	View

Data ID	Experiment type	Sample number	Platform
GSE121385	RNA-seq	6	Illumina HiSeq 2500 (Homo sapiens)
GSE120375	RNA-seq	24	Illumina HiSeq 2500 (Homo sapiens)
GSE175797	RNA-seq	6	Illumina NextSeq 500 (Homo sapiens)