Gene Information
|
Gene Name
|
IL1RAPL1 |
|
Gene ID
|
11141
|
|
Gene Full Name
|
interleukin 1 receptor accessory protein like 1 |
|
Gene Alias
|
IL-1-RAPL-1|IL-1RAPL-1|IL1R8|IL1RAPL|IL1RAPL-1|MRX10|MRX21|MRX34|OPHN4|TIGIRR-2 |
|
Transcripts
|
ENSG00000169306
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins |
|
Uniport_ID
|
Q9NZN1
|
|
HGNC ID
|
HGNC:5996
|
|
OMIM ID
|
300206 |
|
Summary
|
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017] |
Target gene [IL1RAPL1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6016023 |
chrX |
11 |
2 |
0 |
13 |
View |
| 6016024 |
chrX |
11 |
2 |
0 |
13 |
View |
| 6018259 |
chrX |
1 |
8 |
0 |
9 |
View |
| 6020793 |
chrX |
0 |
2 |
4 |
6 |
View |
| 6024718 |
chrX |
2 |
1 |
0 |
3 |
View |
| 6025519 |
chrX |
1 |
1 |
1 |
3 |
View |
| 6027842 |
chrX |
0 |
0 |
1 |
1 |
View |
| 6029866 |
chrX |
1 |
0 |
0 |
1 |
View |
| 6031434 |
chrX |
0 |
0 |
0 |
0 |
View |
Target gene [IL1RAPL1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - IL1RAPL1 peak across samples
|
Peak Plot
|
|
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HTLV1 Target gene Detail Information
