Gene Information
|
Gene Name
|
IRF9 |
|
Gene ID
|
10379
|
|
Gene Full Name
|
interferon regulatory factor 9 |
|
Gene Alias
|
IRF-9|ISGF3|ISGF3G|p48 |
|
Transcripts
|
ENSG00000213928
|
|
Virus
|
MCV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
|
Uniport_ID
|
Q00978
|
|
HGNC ID
|
HGNC:6131
|
|
OMIM ID
|
147574 |
|
Summary
|
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Mutations in this gene result in Immunodeficiency 65. [provided by RefSeq, Jul 2020] |
Target gene [IRF9] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
39110744 |
R102A |
Small T
|
MCPyV_gp4
|
Cell line
|
I
T
|
View |
Target gene [IRF9] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE147406
|
Chip-seq |
39 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE124856
|
Chip-seq |
8 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE226438
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE69877
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
C GSE230758
|
Chip-seq |
20 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE118056
|
scRNA-seq |
4 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE147406 - IRF9 peak across samples
|
Peak Plot
|
> Dataset: GSE124856 - IRF9 peak across samples
|
Peak Plot
|
> Dataset: GSE69877 - IRF9 peak across samples
|
Peak Plot
|
> Dataset: GSE230758 - IRF9 peak across samples
|
Peak Plot
|
|
|