Gene Information
|
Gene Name
|
KALRN |
|
Gene ID
|
8997
|
|
Gene Full Name
|
kalirin RhoGEF kinase |
|
Gene Alias
|
ARHGEF24|CHD5|CHDS5|DUET|DUO|HAPIP|KALNC2|TRAD |
|
Transcripts
|
ENSG00000160145
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Cytosol; 
|
|
Membrane Info
|
Cancer-related genes, Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
O60229
|
|
HGNC ID
|
HGNC:4814
|
|
OMIM ID
|
604605 |
|
Summary
|
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016] |
Target gene [KALRN] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6002774 |
chr3 |
60 |
145 |
5 |
210 |
View |
| 6007148 |
chr3 |
38 |
2 |
19 |
59 |
View |
| 6007149 |
chr3 |
38 |
2 |
19 |
59 |
View |
| 6015783 |
chr3 |
13 |
0 |
0 |
13 |
View |
| 6018905 |
chr3 |
8 |
0 |
0 |
8 |
View |
| 6026754 |
chr3 |
1 |
1 |
0 |
2 |
View |
| 6032162 |
chr3 |
0 |
0 |
0 |
0 |
View |
Target gene [KALRN] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - KALRN peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
