Gene Information
|
Gene Name
|
KAZN |
|
Gene ID
|
23254
|
|
Gene Full Name
|
kazrin, periplakin interacting protein |
|
Gene Alias
|
C1orf196|KAZ |
|
Transcripts
|
ENSG00000189337
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Nuclear speckles, Cytosol; 
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
Q674X7
|
|
HGNC ID
|
HGNC:29173
|
|
OMIM ID
|
618301 |
|
Summary
|
This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011] |
Target gene [KAZN] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6005985 |
chr1 |
48 |
20 |
9 |
77 |
View |
| 6006320 |
chr1 |
9 |
11 |
51 |
71 |
View |
| 6013812 |
chr1 |
13 |
3 |
2 |
18 |
View |
| 6015094 |
chr1 |
9 |
2 |
4 |
15 |
View |
| 6016336 |
chr1 |
4 |
0 |
8 |
12 |
View |
| 6016438 |
chr1 |
12 |
0 |
0 |
12 |
View |
| 6017153 |
chr1 |
5 |
6 |
0 |
11 |
View |
| 6018777 |
chr1 |
4 |
3 |
2 |
9 |
View |
| 6022671 |
chr1 |
4 |
1 |
0 |
5 |
View |
| 6026774 |
chr1 |
0 |
2 |
0 |
2 |
View |
| 6029254 |
chr1 |
1 |
0 |
0 |
1 |
View |
| 6031632 |
chr1 |
0 |
0 |
0 |
0 |
View |
| 6032132 |
chr1 |
0 |
0 |
0 |
0 |
View |
Target gene [KAZN] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - KAZN peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
