Gene Information
|
Gene Name
|
KCNJ6 |
|
Gene ID
|
3763
|
|
Gene Full Name
|
potassium inwardly rectifying channel subfamily J member 6 |
|
Gene Alias
|
BIR1|GIRK-2|GIRK2|KATP-2|KATP2|KCNJ7|KIR3.2|KPLBS|hiGIRK2 |
|
Transcripts
|
ENSG00000157542
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels |
|
Uniport_ID
|
P48051
|
|
HGNC ID
|
HGNC:6267
|
|
OMIM ID
|
600877 |
|
Summary
|
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015] |
Target gene [KCNJ6] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6007008 |
chr21 |
43 |
16 |
1 |
60 |
View |
| 6009027 |
chr21 |
33 |
7 |
0 |
40 |
View |
| 6009477 |
chr21 |
10 |
0 |
27 |
37 |
View |
| 6012198 |
chr21 |
18 |
3 |
2 |
23 |
View |
| 6015659 |
chr21 |
14 |
0 |
0 |
14 |
View |
| 6020105 |
chr21 |
5 |
2 |
0 |
7 |
View |
| 6027239 |
chr21 |
2 |
0 |
0 |
2 |
View |
Target gene [KCNJ6] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - KCNJ6 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
