Gene Information
|
Gene Name
|
KPNA6 |
|
Gene ID
|
23633
|
|
Gene Full Name
|
karyopherin subunit alpha 6 |
|
Gene Alias
|
IPOA7 |
|
Transcripts
|
ENSG00000025800
|
|
Virus
|
IV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;Nucleoplasm; 
|
|
Membrane Info
|
Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
O60684
|
|
HGNC ID
|
HGNC:6399
|
|
OMIM ID
|
610563 |
|
Summary
|
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008] |
Target gene [KPNA6] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [KPNA6] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE225706
|
Chip-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE135069
|
RNA-seq |
10 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE113702
|
Chip-seq |
52 |
Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens) |
|
GSE191176
|
scRNA-seq |
6 |
Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE225704
|
ATAC-seq |
3 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE156060
|
Chip-seq;RNA-seq |
28 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE225706 - KPNA6 peak across samples
|
Peak Plot
|
> Dataset: GSE113702 - KPNA6 peak across samples
|
Peak Plot
|
> Dataset: GSE225704 - KPNA6 peak across samples
|
Peak Plot
|
> Dataset: GSE156060 - KPNA6 peak across samples
|
Peak Plot
|
|
|
IV Target gene Detail Information
