HTLV1 Target gene Detail Information

> LDB2 Gene Search Result


Gene Information
Gene Name LDB2
Gene ID 9079
Gene Full Name LIM domain binding 2
Gene Alias CLIM1|LDB-2|LDB1
Transcripts ENSG00000169744
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nucleoli;Plasma membrane;
Membrane Info Predicted intracellular proteins
Uniport_ID O43679
HGNC ID HGNC:6533
OMIM ID 603450
Summary The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Target gene [LDB2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6008682 chr4 15 0 28 43 View
6012313 chr4 22 1 0 23 View
6013199 chr4 6 11 3 20 View
6013675 chr4 10 8 0 18 View

Target gene [LDB2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - LDB2 peak across samples

Peak Plot