HTLV1 Target gene Detail Information

> LRBA Gene Search Result


Gene Information
Gene Name LRBA
Gene ID 987
Gene Full Name LPS responsive beige-like anchor protein
Gene Alias BGL|CDC4L|CVID8|LAB300|LBA|uc.147
Transcripts ENSG00000198589
Virus HTLV1
Gene Type protein-coding
HPA Location Info Golgi apparatus;Cytosol;
Membrane Info Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P50851
HGNC ID HGNC:1742
OMIM ID 606453
Summary The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Target gene [LRBA] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005754 chr4 36 31 14 81 View
6012928 chr4 5 16 0 21 View
6015022 chr4 12 3 0 15 View
6016693 chr4 2 9 1 12 View
6017499 chr4 9 1 0 10 View
6017604 chr4 0 10 0 10 View
6017823 chr4 4 5 1 10 View
6027810 chr4 0 1 0 1 View
6029938 chr4 0 0 1 1 View
6029965 chr4 0 1 0 1 View

Target gene [LRBA] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - LRBA peak across samples

Peak Plot