Gene Name	LRRC7
Gene ID	57554
Gene Full Name	leucine rich repeat containing 7
Gene Alias	DENSIN
Transcripts	ENSG00000033122
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Plasma membrane, Cytosol;Nucleoplasm, Centrosome;
Membrane Info	Predicted intracellular proteins
HGNC ID	HGNC:18531
OMIM ID	614453
Summary	Predicted to enable protein kinase binding activity. Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; protein localization to postsynapse; and receptor clustering. Located in several cellular components, including centrosome; cytosol; and nucleoplasm. Implicated in cocaine dependence. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001560	chr1	391	5	0	396	View
6018354	chr1	4	3	2	9	View
6023811	chr1	1	3	0	4	View
6025764	chr1	3	0	0	3	View
6026783	chr1	0	2	0	2	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - LRRC7 peak across samples

Peak Plot