Gene Name	MAP3K13
Gene ID	9175
Gene Full Name	mitogen-activated protein kinase kinase kinase 13
Gene Alias	LZK|MEKK13|MLK
Transcripts	ENSG00000073803
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Centriolar satellite;Nucleoplasm, Cytosol;
Membrane Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	O43283
HGNC ID	HGNC:6852
OMIM ID	604915
Summary	The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002427	chr3	22	176	77	275	View
1002439	chr3	24	173	75	272	View
1006487	chr3	30	7	0	37	View
1022252	chr3	30	7	0	37	View
1042812	chr3	37	14	0	51	View
1042813	chr3	84	55	7	146	View
1042814	chr3	84	52	8	144	View

Data ID	Experiment type	Sample number	Platform
GSE252863	scRNA-seq	10	Illumina HiSeq 2500 (Homo sapiens)
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
GSE199850	scRNA-seq	1	HiSeq X Ten (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - MAP3K13 peak across samples

Peak Plot

> Dataset: GSE68402 - MAP3K13 peak across samples

Peak Plot

> Dataset: GSE270130 - MAP3K13 peak across samples

Peak Plot

> Dataset: GSE100400 - MAP3K13 peak across samples

Peak Plot

> Dataset: GSE131257 - MAP3K13 peak across samples

Peak Plot