HTLV1 Target gene Detail Information

> MCF2L Gene Search Result


Gene Information
Gene Name MCF2L
Gene ID 23263
Gene Full Name MCF.2 cell line derived transforming sequence like
Gene Alias ARHGEF14|DBS|OST
Transcripts ENSG00000126217
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Predicted intracellular proteins
Uniport_ID O15068
HGNC ID HGNC:14576
OMIM ID 609499
Summary This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Target gene [MCF2L] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003705 chr13 95 42 8 145 View
6007894 chr13 47 1 3 51 View
6011504 chr13 25 1 0 26 View
6019231 chr13 5 3 0 8 View

Target gene [MCF2L] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - MCF2L peak across samples

Peak Plot