Gene Information
|
Gene Name
|
MGAT4A |
|
Gene ID
|
11320
|
|
Gene Full Name
|
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A |
|
Gene Alias
|
GNT-IV|GNT-IVA|GnT-4a |
|
Transcripts
|
ENSG00000071073
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Golgi apparatus;Secreted to blood;
|
|
Membrane Info
|
Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins |
|
Uniport_ID
|
Q9UM21
|
|
HGNC ID
|
HGNC:7047
|
|
OMIM ID
|
604623 |
|
Summary
|
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008] |
Target gene [MGAT4A] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6002115 |
chr2 |
100 |
100 |
84 |
284 |
View |
| 6005521 |
chr2 |
85 |
0 |
0 |
85 |
View |
| 6007411 |
chr2 |
53 |
2 |
1 |
56 |
View |
Target gene [MGAT4A] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - MGAT4A peak across samples
|
Peak Plot
|
|
|