Gene Name	MGME1
Gene ID	92667
Gene Full Name	mitochondrial genome maintenance exonuclease 1
Gene Alias	C20orf72|DDK1|MTDPS11|bA504H3.4
Transcripts	ENSG00000125871
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Mitochondria;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID	Q9BQP7
HGNC ID	HGNC:16205
OMIM ID	615076
Summary	The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003726	chr20	48	80	16	144	View
6008558	chr20	43	1	0	44	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - MGME1 peak across samples

Peak Plot