Gene Information
|
Gene Name
|
MIR122 |
|
Gene ID
|
406906
|
|
Gene Full Name
|
microRNA 122 |
|
Gene Alias
|
MIR122A|MIRN122|MIRN122A|hsa-mir-122|miRNA122|miRNA122A|mir-122 |
|
Transcripts
|
ENSG00000284440
|
|
Virus
|
HCV |
|
Gene Type
|
ncRNA |
|
HGNC ID
|
HGNC:31501
|
|
OMIM ID
|
609582 |
|
miRBase ID
|
MI0000442
|
|
miRBase Name
|
hsa-mir-122
|
|
Summary
|
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] |
Target gene [MIR122] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [MIR122] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
E GSE126831
|
RNA-seq |
63 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE103730
|
Chip-seq;RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE103728
|
Chip-seq |
24 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE67848
|
RNA-seq |
12 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE211161
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE126831 - MIR122 expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
HCV Target gene Detail Information
