HTLV1 Target gene Detail Information

> MLLT3 Gene Search Result


Gene Information
Gene Name MLLT3
Gene ID 4300
Gene Full Name MLLT3 super elongation complex subunit
Gene Alias AF9|YEATS3
Transcripts ENSG00000171843
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID P42568
HGNC ID HGNC:7136
OMIM ID 159558
Summary Enables chromatin binding activity; lysine-acetylated histone binding activity; and molecular adaptor activity. Involved in several processes, including hematopoietic stem cell differentiation; positive regulation of DNA-templated transcription; and regulation of stem cell division. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of Wnt signaling pathway, planar cell polarity pathway. Located in cytosol and nucleoplasm. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [MLLT3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6016282 chr9 12 0 0 12 View
6021056 chr9 3 3 0 6 View
6032893 chr9 0 0 0 0 View

Target gene [MLLT3] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - MLLT3 peak across samples

Peak Plot