Gene Name	NBEA
Gene ID	26960
Gene Full Name	neurobeachin
Gene Alias	BCL8B|LYST2|NEDEGE
Transcripts	ENSG00000172915
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Golgi apparatus;Cytosol;
Membrane Info	Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8NFP9
HGNC ID	HGNC:7648
OMIM ID	604889
Summary	This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004725	chr13	98	8	0	106	View
6010846	chr13	26	3	0	29	View
6012489	chr13	1	16	5	22	View
6022054	chr13	4	1	0	5	View
6023990	chr13	3	1	0	4	View
6025567	chr13	0	3	0	3	View
6025714	chr13	3	0	0	3	View
6027207	chr13	2	0	0	2	View
6027208	chr13	2	0	0	2	View
6027726	chr13	2	0	0	2	View
6028767	chr13	0	0	1	1	View
6029045	chr13	0	0	1	1	View
6031829	chr13	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - NBEA peak across samples

Peak Plot