HBV Target gene Detail Information

> NFYB Gene Search Result


Gene Information
Gene Name NFYB
Gene ID 4801
Gene Full Name nuclear transcription factor Y subunit beta
Gene Alias CBF-A|CBF-B|HAP3|NF-YB
Transcripts ENSG00000120837
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Predicted intracellular proteins, Transcription factors
Uniport_ID P25208
HGNC ID HGNC:7805
OMIM ID 189904
Summary The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]
Target gene [NFYB] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36257516 N98T
PreS1
S
Occult HBV Infection
G
I
L
T
 View

Target gene [NFYB] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1039224 chr12 186 217 344 747 View
1039225 chr12 196 218 344 758 View
1039226 chr12 199 218 344 761 View
1039227 chr12 201 218 344 763 View
1039228 chr12 202 218 344 764 View
1039229 chr12 208 218 344 770 View
1039230 chr12 211 218 344 773 View
1039231 chr12 214 218 344 776 View
1039232 chr12 236 218 344 798 View
1039233 chr12 242 218 344 804 View
1039234 chr12 243 218 344 805 View
1039235 chr12 246 218 344 808 View
1039236 chr12 259 218 344 821 View
1039237 chr12 262 218 345 825 View
1039238 chr12 266 219 345 830 View
1039239 chr12 267 219 345 831 View

Target gene [NFYB] related to Omics data
Data ID Experiment type Sample number Platform
GSE252863 scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - NFYB expression across samples

Volcano Plot

Bar Plot