HTLV1 Target gene Detail Information

> NHLRC1 Gene Search Result


Gene Information
Gene Name NHLRC1
Gene ID 378884
Gene Full Name NHL repeat containing E3 ubiquitin protein ligase 1
Gene Alias EPM2A|EPM2B|MALIN|MELF2|bA204B7.2
Transcripts ENSG00000187566
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q6VVB1
HGNC ID HGNC:21576
OMIM ID 608072
Summary The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).[provided by RefSeq, Mar 2010]
Target gene [NHLRC1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000195 chr6 2519 395 224 3138 View

Target gene [NHLRC1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - NHLRC1 peak across samples

Peak Plot