Gene Name	OPCML
Gene ID	4978
Gene Full Name	opioid binding protein/cell adhesion molecule like
Gene Alias	IGLON1|OBCAM|OPCM
Transcripts	ENSG00000183715
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Intracellular and membrane;
Membrane Info	Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q14982
HGNC ID	HGNC:8143
OMIM ID	600632
Summary	This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007374	chr11	24	3	1	28	View
1010474	chr11	5	4	3	12	View
1014834	chr11	2	1	0	3	View
1019847	chr11	0	0	0	0	View
1020445	chr11	69	8	0	77	View
1020545	chr11	1	4	0	5	View
1041047	chr11	29	2	2	33	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
GSE270937	DNA methylation sequencing	35	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - OPCML peak across samples

Peak Plot

> Dataset: GSE68402 - OPCML peak across samples

Peak Plot

> Dataset: GSE270130 - OPCML peak across samples

Peak Plot

> Dataset: GSE100400 - OPCML peak across samples

Peak Plot

> Dataset: GSE131257 - OPCML peak across samples

Peak Plot