HTLV1 Target gene Detail Information

> ORC6 Gene Search Result


Gene Information
Gene Name ORC6
Gene ID 23594
Gene Full Name origin recognition complex subunit 6
Gene Alias ORC6L
Transcripts ENSG00000091651
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nucleoli fibrillar center;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q9Y5N6
HGNC ID HGNC:17151
OMIM ID 607213
Summary The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]
Target gene [ORC6] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6010546 chr16 17 13 0 30 View
6010547 chr16 17 13 0 30 View
6011537 chr16 23 0 3 26 View

Target gene [ORC6] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ORC6 peak across samples

Peak Plot