Gene Name	OTUD7A
Gene ID	161725
Gene Full Name	OTU deubiquitinase 7A
Gene Alias	C15orf16|C16ORF15|CEZANNE2|NEDHS|OTUD7
Transcripts	ENSG00000169918
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Cytosol;Nucleoli;
Membrane Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	Q8TE49
HGNC ID	HGNC:20718
OMIM ID	612024
Summary	The protein encoded by this gene is a deubiquitinizing enzyme and possible tumor suppressor. The encoded protein acts on TNF receptor associated factor 6 (TRAF6) to control nuclear factor kappa B expression. However, this gene is downregulated by SNAIL1 in hepatocellular carcinoma cells, contributing to their progression and malignancy. [provided by RefSeq, Aug 2016]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008465	chr15	15	10	20	45	View
6010774	chr15	28	1	0	29	View
6011186	chr15	23	4	0	27	View
6017424	chr15	9	1	0	10	View
6018512	chr15	1	3	5	9	View
6031567	chr15	0	0	0	0	View
6032358	chr15	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - OTUD7A peak across samples

Peak Plot