Gene Information
|
Gene Name
|
PDE11A |
|
Gene ID
|
50940
|
|
Gene Full Name
|
phosphodiesterase 11A |
|
Gene Alias
|
PPNAD2 |
|
Transcripts
|
ENSG00000128655
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Microtubules, Primary cilium;Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q9HCR9
|
|
HGNC ID
|
HGNC:8773
|
|
OMIM ID
|
604961 |
|
Summary
|
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Target gene [PDE11A] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6008713 |
chr2 |
40 |
2 |
0 |
42 |
View |
| 6024821 |
chr2 |
0 |
1 |
2 |
3 |
View |
| 6026677 |
chr2 |
0 |
2 |
0 |
2 |
View |
| 6029948 |
chr2 |
1 |
0 |
0 |
1 |
View |
| 6032667 |
chr2 |
0 |
0 |
0 |
0 |
View |
Target gene [PDE11A] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PDE11A peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
