Gene Information
|
Gene Name
|
PDE1C |
|
Gene ID
|
5137
|
|
Gene Full Name
|
phosphodiesterase 1C |
|
Gene Alias
|
DFNA74|Hcam3|cam-PDE 1C|hCam-3 |
|
Transcripts
|
ENSG00000154678
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Mitochondria, Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q14123
|
|
HGNC ID
|
HGNC:8776
|
|
OMIM ID
|
602987 |
|
Summary
|
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016] |
Target gene [PDE1C] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6009227 |
chr7 |
31 |
7 |
0 |
38 |
View |
| 6013364 |
chr7 |
14 |
5 |
0 |
19 |
View |
| 6014431 |
chr7 |
16 |
0 |
0 |
16 |
View |
| 6023118 |
chr7 |
2 |
2 |
0 |
4 |
View |
| 6026742 |
chr7 |
1 |
1 |
0 |
2 |
View |
| 6028742 |
chr7 |
0 |
1 |
0 |
1 |
View |
| 6029557 |
chr7 |
1 |
0 |
0 |
1 |
View |
| 6032511 |
chr7 |
0 |
0 |
0 |
0 |
View |
Target gene [PDE1C] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PDE1C peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
