HBV Target gene Detail Information

> PDE4D Gene Search Result


Gene Information
Gene Name PDE4D
Gene ID 5144
Gene Full Name phosphodiesterase 4D
Gene Alias ACRDYS2|DPDE3|HSPDE4D|PDE43|PDE4DN2|STRK1
Transcripts ENSG00000113448
Virus HBV
Gene Type protein-coding
HPA Location Info Plasma membrane, Cytosol;Nucleoplasm, Nuclear membrane, Primary cilium;
Membrane Info Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID Q08499
HGNC ID HGNC:8783
OMIM ID 600129
Summary This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Target gene [PDE4D] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002198 chr5 22 223 73 318 View
1005231 chr5 36 10 12 58 View
1005354 chr5 31 10 15 56 View
1009118 chr5 0 14 3 17 View
1009693 chr5 12 0 3 15 View
1009697 chr5 14 1 0 15 View
1013620 chr5 1 2 2 5 View
1013651 chr5 2 2 0 4 View
1014593 chr5 1 2 0 3 View
1014594 chr5 1 2 0 3 View
1041443 chr5 0 0 0 0 View
1041444 chr5 0 0 0 0 View

Target gene [PDE4D] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
S
  GSE247322 		scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
 
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - PDE4D expression across samples

Volcano Plot

Bar Plot