HTLV1 Target gene Detail Information

> PDE4D Gene Search Result


Gene Information
Gene Name PDE4D
Gene ID 5144
Gene Full Name phosphodiesterase 4D
Gene Alias ACRDYS2|DPDE3|HSPDE4D|PDE43|PDE4DN2|STRK1
Transcripts ENSG00000113448
Virus HTLV1
Gene Type protein-coding
HPA Location Info Plasma membrane, Cytosol;Nucleoplasm, Nuclear membrane, Primary cilium;
Membrane Info Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID Q08499
HGNC ID HGNC:8783
OMIM ID 600129
Summary This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Target gene [PDE4D] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6004387 chr5 84 23 10 117 View
6007728 chr5 48 4 0 52 View
6007729 chr5 48 4 0 52 View
6008327 chr5 23 17 6 46 View
6009517 chr5 36 0 0 36 View
6009634 chr5 16 13 7 36 View
6010486 chr5 29 2 0 31 View
6015027 chr5 11 4 0 15 View
6016776 chr5 9 3 0 12 View
6019127 chr5 0 1 7 8 View
6021198 chr5 3 3 0 6 View
6022858 chr5 4 0 0 4 View
6023123 chr5 0 4 0 4 View
6024664 chr5 3 0 0 3 View
6026991 chr5 1 0 1 2 View
6031712 chr5 0 0 0 0 View

Target gene [PDE4D] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - PDE4D peak across samples

Peak Plot