HTLV1 Target gene Detail Information

> PEMT Gene Search Result


Gene Information
Gene Name PEMT
Gene ID 10400
Gene Full Name phosphatidylethanolamine N-methyltransferase
Gene Alias PEAMT|PEMPT|PEMT2|PLMT|PNMT
Transcripts ENSG00000133027
Virus HTLV1
Gene Type protein-coding
HPA Location Info Endoplasmic reticulum, Mitochondria;Vesicles, Cytosol;
Membrane Info Enzymes, Metabolic proteins, Predicted membrane proteins
Uniport_ID Q9UBM1
HGNC ID HGNC:8830
OMIM ID 602391
Summary Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]
Target gene [PEMT] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6009016 chr17 6 12 22 40 View
6011762 chr17 4 19 2 25 View

Target gene [PEMT] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - PEMT peak across samples

Peak Plot