Gene Name	PHKB
Gene ID	5257
Gene Full Name	phosphorylase kinase regulatory subunit beta
Gene Alias	-
Transcripts	ENSG00000102893
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Golgi apparatus;
Membrane Info	Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID	Q93100
HGNC ID	HGNC:8927
OMIM ID	172490
Summary	Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002073	chr16	251	56	45	352	View
1003388	chr16	119	13	5	137	View
1014127	chr16	4	0	0	4	View
1018357	chr16	0	0	0	0	View
1023328	chr16	119	13	5	137	View
1024576	chr16	51	5	7	63	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
GSE199850	scRNA-seq	1	HiSeq X Ten (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
S   GSE247322	scRNA-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• scRNA data
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.

> Dataset: GSE247322 - Gene expression in cell subsets