Gene Information
|
Gene Name
|
PIEZO2 |
|
Gene ID
|
63895
|
|
Gene Full Name
|
piezo type mechanosensitive ion channel component 2 |
|
Gene Alias
|
C18orf30|C18orf58|DA3|DA5|DAIPT|FAM38B|FAM38B2|HsT748|HsT771|MWKS |
|
Transcripts
|
ENSG00000154864
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Vesicles, Cytosol; 
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
Q9H5I5
|
|
HGNC ID
|
HGNC:26270
|
|
OMIM ID
|
613629 |
|
Summary
|
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014] |
Target gene [PIEZO2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6004512 |
chr18 |
11 |
68 |
34 |
113 |
View |
| 6014066 |
chr18 |
12 |
5 |
0 |
17 |
View |
| 6014962 |
chr18 |
11 |
3 |
1 |
15 |
View |
| 6015933 |
chr18 |
13 |
0 |
0 |
13 |
View |
| 6016875 |
chr18 |
8 |
3 |
0 |
11 |
View |
| 6020422 |
chr18 |
3 |
4 |
0 |
7 |
View |
| 6024232 |
chr18 |
3 |
0 |
0 |
3 |
View |
Target gene [PIEZO2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PIEZO2 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
