Gene Information
|
Gene Name
|
PIK3C2G |
|
Gene ID
|
5288
|
|
Gene Full Name
|
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
|
Gene Alias
|
PI3K-C2-gamma|PI3K-C2GAMMA |
|
Transcripts
|
ENSG00000139144
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Centrosome; 
|
|
Membrane Info
|
Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
O75747
|
|
HGNC ID
|
HGNC:8973
|
|
OMIM ID
|
609001 |
|
Summary
|
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Target gene [PIK3C2G] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6004125 |
chr12 |
111 |
17 |
0 |
128 |
View |
| 6004126 |
chr12 |
111 |
17 |
0 |
128 |
View |
| 6015575 |
chr12 |
14 |
0 |
0 |
14 |
View |
| 6019309 |
chr12 |
5 |
3 |
0 |
8 |
View |
| 6021004 |
chr12 |
4 |
2 |
0 |
6 |
View |
| 6032317 |
chr12 |
0 |
0 |
0 |
0 |
View |
| 6033137 |
chr12 |
0 |
0 |
0 |
0 |
View |
Target gene [PIK3C2G] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PIK3C2G peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
