Gene Information
|
Gene Name
|
PIK3CA |
|
Gene ID
|
5290
|
|
Gene Full Name
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
|
Gene Alias
|
CCM4|CLAPO|CLOVE|CWS5|HMH|MCAP|MCM|MCMTC|PI3K|PI3K-alpha|p110-alpha |
|
Transcripts
|
ENSG00000121879
|
|
Virus
|
IV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Primary cilium, Cytosol;Microtubules, Mitochondria; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins |
|
Uniport_ID
|
P42336
|
|
HGNC ID
|
HGNC:8975
|
|
OMIM ID
|
171834 |
|
Summary
|
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016] |
Target gene [PIK3CA] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
16963558 |
Y89F |
NS1
|
NS
|
Influenza A
|
T
|
View |
Target gene [PIK3CA] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE225706
|
Chip-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE135069
|
RNA-seq |
10 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE113702
|
Chip-seq |
52 |
Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE225704
|
ATAC-seq |
3 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE156060
|
Chip-seq;RNA-seq |
28 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE225706 - PIK3CA peak across samples
|
Peak Plot
|
> Dataset: GSE113702 - PIK3CA peak across samples
|
Peak Plot
|
> Dataset: GSE225704 - PIK3CA peak across samples
|
Peak Plot
|
> Dataset: GSE156060 - PIK3CA peak across samples
|
Peak Plot
|
|
|
IV Target gene Detail Information
