Gene Information
|
Gene Name
|
PIK3CB |
|
Gene ID
|
5291
|
|
Gene Full Name
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
|
Gene Alias
|
P110BETA|PI3K|PI3KBETA|PIK3C1 |
|
Transcripts
|
ENSG00000051382
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nucleoli;Vesicles, Midbody; 
|
|
Membrane Info
|
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins |
|
Uniport_ID
|
P42338
|
|
HGNC ID
|
HGNC:8976
|
|
OMIM ID
|
602925 |
|
Summary
|
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] |
Target gene [PIK3CB] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6002173 |
chr3 |
81 |
179 |
14 |
274 |
View |
| 6012794 |
chr3 |
12 |
9 |
0 |
21 |
View |
| 6014546 |
chr3 |
1 |
11 |
4 |
16 |
View |
Target gene [PIK3CB] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PIK3CB peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
