HTLV1 Target gene Detail Information

> PLEKHA1 Gene Search Result


Gene Information
Gene Name PLEKHA1
Gene ID 59338
Gene Full Name pleckstrin homology domain containing A1
Gene Alias TAPP1
Transcripts ENSG00000107679
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Predicted intracellular proteins
Uniport_ID Q9HB21
HGNC ID HGNC:14335
OMIM ID 607772
Summary This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]
Target gene [PLEKHA1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6012615 chr10 8 14 0 22 View
6013307 chr10 15 4 0 19 View
6014736 chr10 16 0 0 16 View
6017717 chr10 8 1 1 10 View

Target gene [PLEKHA1] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - PLEKHA1 peak across samples

Peak Plot