HBV Target gene Detail Information

> PLPBP Gene Search Result


Gene Information
Gene Name PLPBP
Gene ID 11212
Gene Full Name pyridoxal phosphate binding protein
Gene Alias EPEO1|EPVB6D|PROSC
Transcripts ENSG00000147471
Virus HBV
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID O94903
HGNC ID HGNC:9457
OMIM ID 604436
Summary This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017]
Target gene [PLPBP] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1024359 chr8 52 0 0 52 View

Target gene [PLPBP] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
GSE247322 scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - PLPBP peak across samples

Peak Plot

> Dataset: GSE68402 - PLPBP peak across samples

Peak Plot

> Dataset: GSE270130 - PLPBP peak across samples

Peak Plot

> Dataset: GSE131257 - PLPBP peak across samples

Peak Plot