HTLV1 Target gene Detail Information

> POLK Gene Search Result


Gene Information
Gene Name POLK
Gene ID 51426
Gene Full Name DNA polymerase kappa
Gene Alias DINB1|DINP|POLQ
Transcripts ENSG00000122008
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9UBT6
HGNC ID HGNC:9183
OMIM ID 605650
Summary This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]
Target gene [POLK] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6013603 chr5 18 1 0 19 View
6014128 chr5 13 4 0 17 View
6023003 chr5 4 0 0 4 View

Target gene [POLK] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - POLK peak across samples

Peak Plot