HTLV1 Target gene Detail Information

> POU2F3 Gene Search Result


Gene Information
Gene Name POU2F3
Gene ID 25833
Gene Full Name POU class 2 homeobox 3
Gene Alias Epoc-1|OCT-11|OCT11|OTF-11|PLA-1|PLA1|Skn-1a
Transcripts ENSG00000137709
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Plasma membrane, Cytosol;
Membrane Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q9UKI9
HGNC ID HGNC:19864
OMIM ID 607394
Summary This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Target gene [POU2F3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001931 chr11 306 2 5 313 View
6016559 chr11 12 0 0 12 View

Target gene [POU2F3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - POU2F3 peak across samples

Peak Plot