Gene Information
|
Gene Name
|
PPP6R3 |
|
Gene ID
|
55291
|
|
Gene Full Name
|
protein phosphatase 6 regulatory subunit 3 |
|
Gene Alias
|
C11orf23|PP6R3|SAP190|SAPL|SAPLa|SAPS3 |
|
Transcripts
|
ENSG00000110075
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Plasma membrane, Cytosol;
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
Q5H9R7
|
|
HGNC ID
|
HGNC:1173
|
|
OMIM ID
|
610879 |
|
Summary
|
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010] |
Target gene [PPP6R3] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6012272 |
chr11 |
19 |
4 |
0 |
23 |
View |
| 6014957 |
chr11 |
14 |
1 |
0 |
15 |
View |
| 6015925 |
chr11 |
11 |
2 |
0 |
13 |
View |
Target gene [PPP6R3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PPP6R3 peak across samples
|
Peak Plot
|
|
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