Gene Information
|
Gene Name
|
PTPA |
|
Gene ID
|
5524
|
|
Gene Full Name
|
protein phosphatase 2 phosphatase activator |
|
Gene Alias
|
PARK25|PP2A|PPP2R4|PR53 |
|
Transcripts
|
ENSG00000119383
|
|
Virus
|
MCV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Cytosol; 
|
|
Membrane Info
|
Enzymes, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q15257
|
|
HGNC ID
|
HGNC:9308
|
|
OMIM ID
|
600756 |
|
Summary
|
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Target gene [PTPA] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [PTPA] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE147406
|
Chip-seq |
39 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE124856
|
Chip-seq |
8 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE230758
|
Chip-seq |
20 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE69877
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE147406 - PTPA peak across samples
|
Peak Plot
|
> Dataset: GSE124856 - PTPA peak across samples
|
Peak Plot
|
> Dataset: GSE230758 - PTPA peak across samples
|
Peak Plot
|
> Dataset: GSE69877 - PTPA peak across samples
|
Peak Plot
|
|
|
MCV Target gene Detail Information
