Gene Name	PTPN5
Gene ID	84867
Gene Full Name	protein tyrosine phosphatase non-receptor type 5
Gene Alias	PTPSTEP|STEP|STEP61
Transcripts	ENSG00000110786
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P54829
HGNC ID	HGNC:9657
OMIM ID	176879
Summary	Enables phosphotyrosine residue binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in membrane and nucleoplasm. Predicted to be active in cell junction; cytosol; and plasma membrane. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005663	chr11	6	72	5	83	View
6013952	chr11	6	4	8	18	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - PTPN5 peak across samples

Peak Plot