Gene Information
|
Gene Name
|
RAD21 |
|
Gene ID
|
5885
|
|
Gene Full Name
|
RAD21 cohesin complex component |
|
Gene Alias
|
CDLS4|HR21|HRAD21|MCD1|MGS|NXP1|SCC1|hHR21 |
|
Transcripts
|
ENSG00000164754
|
|
Virus
|
DENV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins |
|
Uniport_ID
|
O60216
|
|
HGNC ID
|
HGNC:9811
|
|
OMIM ID
|
606462 |
|
Summary
|
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008] |
Target gene [RAD21] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
36514984 |
I114T |
NS2B
|
NS2B
|
Dengue
|
G
R
T
|
View |
Target gene [RAD21] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE152255
|
RNA-seq |
99 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE155672
|
RNA-seq |
12 |
HiSeq X Ten (Homo sapiens) |
|
GSE154386
|
scRNA-seq |
30 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE110511
|
Chip-seq |
24 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE132367
|
RNA-seq |
57 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE279208
|
RNA-seq |
26 |
DNBSEQ-G400 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE110511 - RAD21 peak across samples
|
Peak Plot
|
|
|