Gene Information
|
Gene Name
|
RAD51B |
|
Gene ID
|
5890
|
|
Gene Full Name
|
RAD51 paralog B |
|
Gene Alias
|
R51H2|RAD51L1|REC2 |
|
Transcripts
|
ENSG00000182185
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nuclear bodies;Nucleoplasm; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
O15315
|
|
HGNC ID
|
HGNC:9822
|
|
OMIM ID
|
602948 |
|
Summary
|
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016] |
Target gene [RAD51B] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6003268 |
chr14 |
155 |
11 |
5 |
171 |
View |
| 6005119 |
chr14 |
43 |
52 |
0 |
95 |
View |
| 6005257 |
chr14 |
74 |
15 |
3 |
92 |
View |
| 6014293 |
chr14 |
16 |
0 |
1 |
17 |
View |
| 6014761 |
chr14 |
0 |
9 |
7 |
16 |
View |
Target gene [RAD51B] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - RAD51B peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
